Juniper Publishers-Nutrition Food Science International Journal

  Abstract Background:  Therapeutic treatment of Sickle cell disease (SCD) is complex and very expensive. However, natural products have been used to manage sickle cell crises. Omega-3 fatty acids EPA/DHA reduce the number of crisis in SCD. Objectives:  This study aimed to assess the antisickling and antioxidant properties of omega-3 fatty acids EPA/DHA. Methods:  The evaluation of the rates of inhibition of induced sickling by sodium metabisulfite 2% and the potential reversal of sickle cells into normal spherical erythrocytes was performed using microscopic enumeration of red blood corpuscles of the sickling. The evaluation of membrane stability effect, FRAP, DPPH°, and OH° assays was determined using colorimetric method. Results:  Sodium metabisulfite increased the sickling of RBCs from 26.3±1.6 to 79.42±5.2% during 3 hours. Omega-3 fatty acids EPA/DHA 0.2% showed the best antisickling (79.05±1.2%) and reversibility (64.82± 2.7%) rate; the best membrane stabi...

Nutrition & Food Science - Juniper Publishers Abstract Cardiovascular diseases stand out in terms of high mortality and the association of various cardiovascular risk factors. It is inferred that these involve a context of care with the interrelation of factors that accompany a situation of individual and/or collective cardiovascular vulnerability. This context demands a review and clarification of concepts and the development-based care protocols are in theory s to guide health policies and targeted assistance programs for health promotion and cardiovascular disease prevention in the world. Keywords:   Cardiovascular risk; Context; Care; Health; Prevention of diseases; Promotion of Health. Opinion Cardiovascular diseases stand out in terms of high mortality and the association of various cardiovascular risk factors, being the main cause of death in the world, with more than three quarters of these occurring in low- and middle-income countries [1]...